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HelpTest Code COU Cobalt, 24 Hour, Urine
Reporting Name
Cobalt, 24 Hr, UUseful For
Detecting cobalt exposure
Monitoring metallic prosthetic implant wear
This test is not useful to assess vitamin B12 activity.
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineOrdering Guidance
High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert
Submission Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 0.5 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
3. See Metals Analysis Specimen Collection and Transport for complete instructions.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
An entire 24-hour urine collection is also acceptable.
Note: 1. Starting and ending times of collection are required.
2. Follow instructions in Urine Collection in Specimen Collection and Preparation in General Information.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Ambient | 28 days | ||
| Frozen | 28 days |
Special Instructions
Reference Values
0-17 years: Not established
≥18 years: 0.2-3.5 mcg/24 hours
Day(s) Performed
Tuesday, Wednesday, Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83018
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| COU | Cobalt, 24 Hr, U | 29916-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80083 | Cobalt, 24 Hr, U | 29916-4 |
| TM75 | Collection Duration | 13362-9 |
| VL64 | Urine Volume | 3167-4 |
Report Available
1 to 4 daysMethod Name
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)